Autologous Platelet-Rich Plasma (PRP)

Millions of people, including athletes and physically active individuals, enjoy sports as a way of life. Regular physical activity and daily movement, however, can lead to pain and musculoskeletal injuries that limit and hinder daily functioning.

More than 600 clinical studies registered on PubMed investigate the effectiveness of Platelet-Rich Plasma (PRP) therapy. This autologous treatment has been evaluated across various medical specialties including physical medicine and rehabilitation, sports medicine, orthopedics, regenerative and wound healing medicine, neurosurgery, dentistry, ophthalmology, as well as aesthetic, plastic, maxillofacial, and cardiovascular surgery.

Regen Lab developed RegenKit® technology as the optimal solution for obtaining autologous platelet-rich plasma from venous blood.

What is Platelet-Rich Plasma (PRP)?

PRP therapy offers a highly promising biological solution to accelerate the healing of tendon injuries, muscle strains, and early-stage osteoarthritis naturally and without associated risks.

Platelet-rich plasma is a concentration of human platelets in a small volume of plasma. Platelets act as carriers of growth factors (PDGF, TGF-β, IGF, EGF, VEGF), which stimulate the proliferation of fibroblasts, osteoblasts, and endothelial cells to promote and accelerate the healing of both hard and soft tissues (e.g., collagen, tendons, muscles, ligaments, bones, skin).

Platelets are cells well-known for their role in blood clotting. When activated in the body, they release healing proteins known as growth factors. These growth factors act synergistically to speed up tissue repair.

 

How is the Procedure Performed?

The procedure is as follows: a small quantity of blood (4–5 cc) is drawn from the patient—similar to a standard blood test—and placed into a specialized container. It is then centrifuged for 5 minutes to isolate the plasma containing the platelets.

The platelets are then activated using calcium chloride (DNA activator) to release their stored growth factors (PDGF, TGF-β, VEGF, EGF, FGF, IGF-1) through a process called degranulation.

The injection can also be performed under ultrasound guidance for maximum precision. Platelets continue producing and releasing growth factors for approximately the first 7 days following activation.

Where is the Procedure Performed?

The entire process takes approximately 30 minutes, is performed on-site at the clinic, and is completed within the same session. No hospitalization or special post-treatment precautions are required. Since only the patient’s own blood is used, there is no risk of allergy or hypersensitivity. The procedure can be repeated after one week, and depending on the severity of the condition, up to three injections may be administered.

Results from international literature are very encouraging, as the method is now widely used. PRP injections have been proven to relieve both acute and chronic pain, and accelerate the healing of injured tissues and joints. As a result, patients and athletes experience faster recovery and return to their daily activities.

Advantages of the Method

  • Simple and quick procedure

  • Only a small volume of blood required

  • Optimal platelet yield

  • Isolated PRP with specific characteristics, free of red blood cells

For all applicable cases, autologous Platelet-Rich Plasma (PRP) injections offer the following benefits:

  • Promote and accelerate the natural healing process by enhancing cellular regeneration

  • Significantly reduce pain

  • Offer a natural alternative to conventional treatments (e.g., medications, corticosteroid injections)

  • Eliminate the risks of immune reactions or infections from transmissible diseases

  • Can be combined with other regenerative therapies such as Extracorporeal Shockwave Therapy and K-Laser Therapy

PRP Therapy is Used for the Following Conditions:

Shoulder

  • Early-stage osteoarthritis

  • Tendonitis and partial tears of the rotator cuff

  • Inflammation or arthritis of the acromioclavicular joint

  • Biceps tendonitis

Elbow

  • Early-stage osteoarthritis

  • Lateral epicondylitis (tennis elbow)

  • Medial epicondylitis (golfer’s elbow)

  • Ulnar collateral ligament sprain or tear

Wrist / Hand

  • de Quervain’s tenosynovitis

  • Thumb sprain

Hip / Pelvis

  • Early-stage osteoarthritis

  • Trochanteric bursitis

  • Sacroiliac joint pain

  • Pubic osteitis, adductor syndrome, quadriceps, hamstring, and popliteal strains

Knee

  • Early-stage osteoarthritis

  • Chondropathy

  • Patellar chondromalacia

  • Quadriceps or patellar tendonitis

  • Ligament sprains or partial tears

  • Iliotibial band syndrome

  • Tibial periostitis (shin splints)

Ankle / Foot

  • Early-stage osteoarthritis

  • Chondropathy

  • Ankle sprain

  • Achilles tendonitis

  • Plantar fasciitis (heel spur)

  • Peroneal tendonitis

Wound Healing

  • Diabetic ulcers

  • Pressure ulcers (bedsores)